Affordable Access

deepdyve-link
Publisher Website

Solid-phase synthesis of 2-pyridones, 1,4-diazepines, and 1,4-oxazepines from resin-bound 3-amino-2-seleno ester.

Authors
  • Xu, Jian-Feng
  • Huang, Xian
Type
Published Article
Journal
Journal of Combinatorial Chemistry
Publisher
American Chemical Society
Publication Date
Jan 01, 2009
Volume
11
Issue
5
Pages
938–942
Identifiers
DOI: 10.1021/cc900086e
PMID: 19691355
Source
Medline
License
Unknown

Abstract

A versatile combinatorial approach was developed for the rapid synthesis of 2-pyridones, 1,4-diazepines, and 1,4-oxazepines libraries. The synthetic strategy includes electrophilic addition, nucleophilic substitution, amine-acid condensation, Dieckmann condensation, lactamization, ester hydrolysis, lactonization, and oxidation-elimination.

Report this publication

Statistics

Seen <100 times