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[Sodium selenite reduces acute radiogenic damage of the rat parotid glands during fractionated irradiation].

Authors
  • Sagowski, C
  • Wenzel, S
  • Tesche, S
  • Jenicke, L
  • Kehrl, W
  • Roeser, K
  • Metternich, F U
Type
Published Article
Journal
HNO
Publication Date
Dec 01, 2004
Volume
52
Issue
12
Pages
1067–1075
Identifiers
PMID: 15597168
Source
Medline
License
Unknown

Abstract

Based on morphological and sialoscintigraphic findings, a cytoprotective effect on acute toxicity of rat salivary glands could be detected under irradiation with synchronous application of sodium selenite. In addition, no effects on tumor response and metastasis frequency were observed. The general animal constitution was not affected by additional medication with sodium selenite during irradiation.

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