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Sodium-lithium countertransport: physiology and function.

Authors
Type
Published Article
Journal
Journal of Hypertension
0263-6352
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Volume
16
Issue
1
Pages
3–13
Identifiers
PMID: 9533410
Source
Medline
License
Unknown

Abstract

Current opinions on the relationships between erythrocyte sodium-lithium countertransport kinetics and primary hypertension, hyperlipidaemia and diabetic nephropathy are reviewed. Problems associated with the assay are analysed. Some possible mechanisms that could modify the kinetics of ion exchange are examined. The question of what catalyses sodium-lithium countertransport is discussed, but not answered. Some models are put forward showing how a study of sodium-lithium countertransport kinetics could further our understanding of important disease processes.

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