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SNP-Based Heritability Estimates of Common and Specific Variance in Self- and Informant-Reported Neuroticism Scales.

Authors
  • Realo, Anu1, 2
  • van der Most, Peter J3
  • Allik, Jüri2, 4
  • Esko, Tõnu5
  • Jeronimus, Bertus F3, 6
  • Kööts-Ausmees, Liisi2
  • Mõttus, René2, 7
  • Tropf, Felix C6, 8
  • Snieder, Harold3, 5
  • Ormel, Johan3
  • 1 University of Warwick.
  • 2 University of Tartu.
  • 3 University of Groningen, University Medical Center Groningen.
  • 4 The Estonian Academy of Sciences. , (Estonia)
  • 5 Estonian Genome Centre of University of Tartu. , (Estonia)
  • 6 University of Groningen.
  • 7 University of Edinburgh.
  • 8 Nuffield College, University of Oxford.
Type
Published Article
Journal
Journal of personality
Publication Date
Dec 01, 2017
Volume
85
Issue
6
Pages
906–919
Identifiers
DOI: 10.1111/jopy.12297
PMID: 27977872
Source
Medline
Keywords
License
Unknown

Abstract

Our findings indicate that a large proportion of the heritability of Neuroticism is not captured by additive genetic effects of common SNPs, with some evidence for Gene × Environment interaction across cohorts.

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