Sneddon syndrome: under diagnosed disease, complex clinical manifestations and challenging diagnosis. A case-based review.
University of Central Florida College of Medicine, Orlando, FL, USA.
University of Central Florida HCA Healthcare GME, 6850 Lake Nona Blvd, Orlando, FL, 32827, USA. [email protected]
Department of Internal Medicine, University of Central Florida College of Medicine, Orlando, FL, USA. [email protected]
Department of Internal Medicine, University of Central Florida College of Medicine, Orlando, FL, USA.
- Published Article
- Publication Date
May 01, 2021
Herein, we report a case-based review of the Sneddon Syndrome (SS), a rare chronic condition which affects small to medium blood vessels. It is known by its skin presentation, livedo racemosa (LRC), and the relapsing cerebrovascular events. However, neither LRC nor cerebrovascular events are exclusive to SS. A 36-year-old female with history of mitral valve prolapse, hypothyroidism, Raynaud phenomenon, hypertension, migraines, and four episodes of transient ischemic attacks (TIA), presented to our clinic with new skin findings, suggestive of LRC. Based on her previous history, current presentation and skin biopsy results, she was diagnosed with SS secondary to antiphospholipid syndrome. The present report illustrates the difficulty in recognizing SS and how the heterogeneity of the disease may be contributing to the difficulty making a distinct diagnosis.
Report this publication
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
This record was last updated on 04/18/2021 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/32533291