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A smooth operator for LPS responses

Authors
  • Godowski, Paul J1
  • 1 Genentech, South San Francisco, California, 94080, USA , South San Francisco (United States)
Type
Published Article
Journal
Nature Immunology
Publisher
Springer Nature
Publication Date
Jun 01, 2005
Volume
6
Issue
6
Pages
544–546
Identifiers
DOI: 10.1038/ni0605-544
Source
Springer Nature
License
Yellow

Abstract

The function of CD14 in LPS signaling has remained enigmatic. Examination of the responses of cells and mice with defective CD14 shows that this molecule seems to modulate specific LPS recognition by TLR4.

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