Affordable Access

deepdyve-link
Publisher Website

SMITten by the Speed of Splicing.

Authors
  • Tl, Johnson
  • Jr, Ares M
Type
Published Article
Journal
Cell
Publisher
Elsevier
Volume
165
Issue
2
Pages
265–267
Identifiers
DOI: 10.1016/j.cell.2016.03.035
Source
UCSC Bioinformatics biomedical-ucsc
License
Unknown

Abstract

Splicing occurs co-transcriptionally, but relative rates of splicing and transcription that might reveal mechanisms of their coordinated control have remained mysterious. Now, Carrillo Oesterreich et al. show that the fastest introns are gone nearly as soon as the 3 splice site is transcribed and that introns have distinct splicing kinetics with respect to polymerase progression along the gene.

Report this publication

Statistics

Seen <100 times