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Smart DNA vectors based on cyclodextrin polymers: compaction and endosomal release.

Authors
  • Wintgens, Véronique
  • Leborgne, Christian
  • Baconnais, Sonia
  • Burckbuchler, Virginie
  • Le Cam, Eric
  • Daniel Scherman
  • Kichler, Antoine
  • Amiel, Catherine
Type
Published Article
Journal
Journal of the American Dietetic Association
Publisher
Elsevier
Publication Date
February 2012
Volume
29
Issue
2
Pages
384–396
Identifiers
DOI: 10.1007/s11095-011-0560-0
PMID: 21847694
Source
USPC - SET - SVS
License
Unknown

Abstract

We successfully designed fine-tuned DNA vectors based on cyclodextrin polymers combined with two new adamantyl derivatives, leading to significant transfection associated with low toxicity.

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