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In Situ Controlled Surface Microstructure of 3D Printed Ti Alloy to Promote Its Osteointegration

Authors
  • Shan, Lijun
  • Kadhum, Abdul Amir H.
  • Al-Furjan, M.S.H.
  • Weng, Wenjian
  • Gong, Youping
  • Cheng, Kui
  • Zhou, Maoying
  • Dong, Lingqing
  • Chen, Guojin
  • Takriff, Mohd S.
  • Sulong, Abu Bakar
Publication Date
Mar 10, 2019
Source
MDPI
Keywords
Language
English
License
Green
External links

Abstract

stripy composite surface (BS) were determined by contour scanning. A nano-sized structure could be superposed by hydrothermal treatment. The cytocompatibility was evaluated by culturing Mouse calvaria-derived preosteoblastic cells (MC3T3-E1). The results showed that three typical microstructured surfaces, S, B, and BS, could be achieved by varying the 3D printing parameters. Moreover, the osteogenic differentiation potential of the S, B, and BS surfaces could be significantly enhanced, and the addition of nano-sized structures could be further improved. The BS surface with nano-sized structure demonstrated the optimum osteogenic differentiation potential. The present research demonstrated an in situ, controlled way to tailor and optimize the surface structures in micro-size during the 3D printing process for an implant with higher osseointegration ability.

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