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Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn’s Disease Reveals Tissue-Specific Characteristics and Drug Targets

Authors
  • Venema, Werna T. Uniken1
  • Voskuil, Michiel D.1
  • Vila, Arnau Vich1, 2
  • van der Vries, Gerben2
  • Jansen, Bernadien H.1
  • Jabri, Bana3
  • Faber, Klaas Nico1, 4
  • Dijkstra, Gerard1
  • Xavier, Ramnik J.5, 6
  • Wijmenga, Cisca2
  • Graham, Daniel B.5, 6
  • Weersma, Rinse K.1
  • Festen, Eleonora A.1, 2
  • 1 Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
  • 2 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
  • 3 Department of Medicine and Committee on Immunology, University of Chicago, Chicago, Illinois
  • 4 Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
  • 5 Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, Massachusetts
  • 6 Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
Type
Published Article
Journal
Gastroenterology
Publication Date
Nov 02, 2018
Volume
156
Issue
3
Pages
812–815
Identifiers
DOI: 10.1053/j.gastro.2018.10.046
PMID: 30391472
PMCID: PMC6759855
Source
PubMed Central
Keywords
License
Unknown
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