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A Single-Cell RNA Expression Map of Human Coronavirus Entry Factors

Authors
  • Singh, Manvendra1
  • Bansal, Vikas2, 3
  • Feschotte, Cédric1
  • 1 Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA
  • 2 Biomedical Data Science and Machine Learning Group, German Center for Neurodegenerative Diseases, Tübingen 72076, Germany
  • 3 Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen 37075, Germany
Type
Published Article
Journal
Cell Reports
Publisher
Elsevier
Publication Date
Sep 03, 2020
Volume
32
Issue
12
Pages
108175–108175
Identifiers
DOI: 10.1016/j.celrep.2020.108175
PMID: 32946807
PMCID: PMC7470764
Source
PubMed Central
Keywords
License
Unknown

Abstract

Singh et al. provide a resource to predict the tropism and identify the plausible entry points for SARS-CoV-2 and other pathogenic coronaviruses throughout the human body. The RNA levels of 28 genes dubbed “SCARFs,” for SARS-CoV-2 and coronavirus-associated receptors and factors, are profiled in human tissues at the single-cell level.

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