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Single step high-throughput determination of Toll-like receptor 4 polymorphisms.

Authors
  • van Rijn, Bas B
  • Roest, Mark
  • Franx, Arie
  • Bruinse, Hein W
  • Voorbij, Hieronymus A M
Type
Published Article
Journal
Journal of Immunological Methods
Publisher
Elsevier
Publication Date
Jun 01, 2004
Volume
289
Issue
1-2
Pages
81–87
Identifiers
PMID: 15251414
Source
Medline
License
Unknown

Abstract

We have developed a novel method for the detection of the TLR4 Asp299Gly and Thr399Ile mutations, permitting rapid genotyping which should be useful for large-scale population studies as well as applicable for routine clinical testing.

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