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Single-nucleotide polymorphisms of mitochondrially coded subunit genes of cytochrome c oxidase in five chicken breeds.

Authors
  • Bao, Haigang
  • Zhao, Chunjiang
  • Zhang, Lifan
  • Li, Junying
  • Wu, Changxin
Type
Published Article
Journal
Mitochondrial DNA
Publication Date
Oct 01, 2008
Volume
19
Issue
5
Pages
461–464
Identifiers
PMID: 19489140
Source
Medline
License
Unknown

Abstract

Cytochrome c oxidase (COX) plays important roles in oxidative phosphorylation regulation and oxygen sensing transfer. In the present study, single-nucleotide polymorphisms (SNPs) in three mitochondrially coded subunit genes of COX were identified with the technique of single-strand conformation polymorphism in Tibet Chicken and four lowland chicken breeds-Dongxiang Chicken, Silky Chicken, Hubbard ISA White broiler, and Leghorn layer. In total, 14 SNPs were identified in the three genes of COX of the five chicken breeds, and 13 haplotypes were defined for the 14 SNPs. This work will afford reference for the further study on the association of COX with the adaptation to hypoxia.

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