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Single chain Fab (scFab) fragment.

Authors
  • Hust, Michael
  • Jostock, Thomas
  • Menzel, Christian
  • Voedisch, Bernd
  • Mohr, Anja
  • Brenneis, Mariam
  • Kirsch, Martina I
  • Meier, Doris
  • Dübel, Stefan
Type
Published Article
Journal
BMC Biotechnology
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Jan 01, 2007
Volume
7
Pages
14–14
Identifiers
PMID: 17346344
Source
Medline
License
Unknown

Abstract

A new antibody design offers the generation of bivalent Fab derivates for antibody phage display and production of soluble antibody fragments. This antibody format is of particular value for high throughput proteome binder generation projects, due to the avidity effect and the possible use of common standard sera for detection.

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