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A simplified physical model of pressure wave dynamics and acoustic wave generation induced by laser absorption in the retina

Authors
  • Till, S. J.1
  • Milsom, P. K.1
  • Rowlands, G.2
  • 1 Defence Science and Technology Laboratory, Malvern, Worcestershire, WR14 3PS, UK , Malvern, Worcestershire
  • 2 University of Warwick, Department of Physics, Coventry, CV4 7AL, UK , Coventry
Type
Published Article
Journal
Bulletin of Mathematical Biology
Publisher
Springer-Verlag
Publication Date
Jul 01, 2004
Volume
66
Issue
4
Pages
791–808
Identifiers
DOI: 10.1016/j.bulm.2003.10.009
Source
Springer Nature
Keywords
License
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Abstract

Shock waves have been proposed in the literature as a mechanism for retinal damage induced by ultra-short laser pulses. For a spherical absorber, we derive a set of linear equations describing the propagation of pressure waves. We show that the formation of shock fronts is due to the form of the absorber rather than the inclusion of nonlinear terms in the equations. The analytical technique used avoids the need for a Laplace transform approach and is easily applied to other absorber profiles. Our analysis suggests that the ’soft’ nature of the membrane surrounding retinal melanosomes precludes shock waves as a mechanism for the retinal damage induced by ultra-short pulse lasers. The quantitative estimates of the pressure gradients induced by laser absorption which are made possible by this work, together with detailed meso-scale or molecular modelling, will allow alternative damage mechanisms to be identified.

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