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Simplified detection of hydrochlorothiazide in urine by thin-layer chromatography.

Authors
Type
Published Article
Journal
Journal of analytical toxicology
Publication Date
Volume
8
Issue
4
Pages
170–172
Identifiers
PMID: 6471816
Source
Medline
License
Unknown

Abstract

A new thin-layer chromatographic procedure for the detection of the antihypertensive/diuretic drug hydrochlorothiazide in human urine is described. The sensitivity of the method, 5 micrograms/mL, makes it useful to both the clinician interested in determining patient compliance and the toxicologist who must identify or confirm hydrochlorothiazide ingestion. The rapidity of analysis typically allows the screening of 25 urine samples within one hour.

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