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Silencing of Eps8 inhibits in vitro angiogenesis.

Authors
Type
Published Article
Journal
Life Sciences
0024-3205
Publisher
Elsevier
Publication Date
Volume
131
Pages
30–36
Identifiers
DOI: 10.1016/j.lfs.2015.03.018
PMID: 25896663
Source
Medline
Keywords
  • Endothelial Cells
  • Eps8
  • In Vitro Angiogenesis
  • Tumor-Derived Endothelial Cells

Abstract

Our data demonstrate for the first time the involvement of Eps8 in the morphological processes required for in vitro angiogenesis, and suggest that this protein might represent a common target for the design of new anticancer drugs, acting at the same time on both tumor and endothelial cells.

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