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Significant association of the cytokine variants with head and neck cancer risk: evidence from meta-analysis.

Authors
  • Xiao, Ting-Ting1, 2
  • Li, Xian2, 3
  • Xu, Ying1, 2
  • Li, Yong4, 5, 6
  • 1 Department of Oral and Maxillofacial Surgery, Stomatological Hospital of Chongqing Medical University, Chongqing, 401147, China. , (China)
  • 2 Chongqing Key Laboratory of Oral Disease and Biomedical Sciences, Chongqing, China. , (China)
  • 3 Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China. , (China)
  • 4 Department of Oral and Maxillofacial Surgery, Stomatological Hospital of Chongqing Medical University, Chongqing, 401147, China. [email protected] , (China)
  • 5 Chongqing Key Laboratory of Oral Disease and Biomedical Sciences, Chongqing, China. [email protected] , (China)
  • 6 Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China. [email protected] , (China)
Type
Published Article
Journal
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Publication Date
Feb 01, 2018
Volume
275
Issue
2
Pages
483–496
Identifiers
DOI: 10.1007/s00405-017-4820-4
PMID: 29185028
Source
Medline
Keywords
License
Unknown

Abstract

It should be a potential association between IL-18 variants and nasopharyngeal carcinoma. Furthermore, IL-18 gene variants might be considered as a critical role in predicting the occurrence of nasopharyngeal carcinoma in Asian population. However, the IL-4-590 C>T polymorphism does not influence the development of head and neck cancer.

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