Affordable Access

deepdyve-link
Publisher Website

Signals from dying hepatocytes trigger growth of liver progenitors.

Authors
  • Jung, Youngmi
  • Witek, Rafal P
  • Syn, Wing-Kin
  • Choi, Steve S
  • Omenetti, Alessia
  • Premont, Richard
  • Guy, Cynthia D
  • Diehl, Anna Mae
Type
Published Article
Journal
Gut
Publisher
BMJ
Publication Date
May 01, 2010
Volume
59
Issue
5
Pages
655–665
Identifiers
DOI: 10.1136/gut.2009.204354
PMID: 20427400
Source
Medline
License
Unknown

Abstract

Dying mature hepatocytes produce Hh ligands which promote the compensatory outgrowth of progenitors and myofibroblasts. These results help to explain why diseases that chronically increase hepatocyte death promote cirrhosis.

Report this publication

Statistics

Seen <100 times