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Signal transduction pathways controlling multicellular development in Dictyostelium.

Authors
Type
Published Article
Journal
Trends in Genetics
0168-9525
Publisher
Elsevier
Publication Date
Volume
7
Issue
11-12
Pages
381–388
Identifiers
PMID: 1668191
Source
Medline
License
Unknown

Abstract

The importance of signal transduction pathways in regulating developmental processes in a number of organisms has become evident in recent years. This is exceptionally clear for Dictyostelium, which uses soluble factors to regulate morphogenesis and cellular differentiation. It is now known that many of these processes are controlled by signal transduction pathways mediated by cyclic AMP through cell surface receptors coupled to G proteins, and that others are mediated by the morphogen DIF.

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