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Sigma receptors on NCB-20 hybrid neurotumor cells labeled with (+)[3H]SKF 10,047 and (+)[3H]3-PPP.

Authors
  • Largent, B L
  • Gundlach, A L
  • Snyder, S H
Type
Published Article
Journal
European Journal of Pharmacology
Publisher
Elsevier
Publication Date
May 13, 1986
Volume
124
Issue
1-2
Pages
183–187
Identifiers
PMID: 3013658
Source
Medline
License
Unknown

Abstract

(+)[3H]SKF 10,047 and (+)[3H]3-PPP label a homogeneous population of sites in NCB-20 cell membranes that apparently represent benzomorphan specific binding sites previously reported for this cell line. Their drug specificity indicates that these sites are very similar to sigma receptor binding sites labeled in brain tissues by these ligands and do not represent PCP receptors.

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