Since the UNDP/World Bank/WHO Special Program for Research and Training in Tropical Diseases (TDR) began, the Liverpool School of Tropical Medicine has been closely involved with the program through steering committees, undertaking projects in Liverpool and abroad, and training students in Liverpool and in-country. The relationship between the school and TDR's activities has evolved in step with the evolution of TDR. The school has always recognized that it must focus upon the developing world and has sought to collaborate with TDR in field projects. The current portfolio of links between Liverpool and TDR is focused upon the disease-related and health system expertise in Liverpool which provides for student supervision associated with institutions in Latin America, Africa, South Asia, and Southeast Asia. With co-funding from TDR and the British government, the school is currently evaluating the impact of health sector reform upon malaria control in 6 districts in Ghana. Other studies and projects upon which the school is working are described.