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Should routine analysis of the MEN1 gene be performed in all patients with primary hyperparathyroidism under 40 years of age?

Authors
  • Skandarajah, Anita
  • Barlier, Anne
  • Morlet-Barlat, Nathalie
  • Sebag, Frederic
  • Enjalbert, Alain
  • Conte-Devolx, Bernard
  • Henry, Jean-François
Type
Published Article
Journal
World Journal of Surgery
Publisher
Springer-Verlag
Publication Date
Jun 01, 2010
Volume
34
Issue
6
Pages
1294–1298
Identifiers
DOI: 10.1007/s00268-009-0388-5
PMID: 20058152
Source
Medline
License
Unknown

Abstract

Although young age is often the only criterion to suspect MEN1, our results do not support routine MEN1 analysis in patients under 40. We propose that these patients be managed with the same preoperative and surgical approach as those presenting with sporadic 1 degrees HPT of any age.

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