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A short-term comparative trial of salsalate and indomethacin in rheumatoid arthritis.

Authors
Type
Published Article
Journal
Current medical research and opinion
Publication Date
Volume
5
Issue
2
Pages
185–188
Identifiers
PMID: 340137
Source
Medline
License
Unknown

Abstract

A short-term, double-blind, placebo-controlled crossover study was completed in 15 patients with classical or definite rheumatoid arthritis to compare the antirheumatic activity of salsalate (3 g/day) with placebo and indomethacin (75 mg/day). Subjective and objective assessments showed that both salsalate and indomethacin were significantly superior to placebo. Grip strength was not improved by either of the drugs. Patient preference was in favour of indomethacin, but the difference between it and salsalate was insignificant.

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