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Short sleep duration increases salivary IL-6 production.

Authors
  • Reinhardt, Érica Lui1
  • Fernandes, Pedro A C M2
  • Markus, Regina P2
  • Fischer, Frida Marina3
  • 1 a National Technical Center , Fundacentro, São Paulo , Brazil. , (Brazil)
  • 2 b Laboratory of Chronopharmacology, Department of Physiology , Institute of Bioscience, University of São Paulo , São Paulo , Brazil. , (Brazil)
  • 3 c Department of Environmental Health, School of Public Health , University of São Paulo , São Paulo , Brazil. , (Brazil)
Type
Published Article
Journal
Chronobiology International
Publisher
Informa UK (Taylor & Francis)
Publication Date
2016
Volume
33
Issue
6
Pages
780–782
Identifiers
DOI: 10.3109/07420528.2016.1167710
PMID: 27070477
Source
Medline
Keywords
License
Unknown

Abstract

Morning shift sleep restriction has been associated with higher plasma IL-6 levels. The aim of this study was to investigate the effect of sleep duration on salivary IL-6. Sleep duration of morning shift workers was estimated by actigraphy. Workers with "longer sleep duration" (LSD; N = 6) and "shorter sleep duration" (SSD; N = 15) were then compared regarding salivary IL-6 levels determined at 14:00 h, bed and wake times. SSD workers did not show daily variation of IL-6 and presented higher levels at bedtime and 14:00 h compared to LSD workers. In this study, SSD is associated with an increase in salivary IL-6 content.

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