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Shifting in balance between osteogenesis and adipogenesis substantially influences hematopoiesis.

Authors
  • Sugimura, Ryohichi
  • Li, Linheng
Type
Published Article
Journal
Journal of molecular cell biology
Publication Date
Apr 01, 2010
Volume
2
Issue
2
Pages
61–62
Identifiers
DOI: 10.1093/jmcb/mjp030
PMID: 19833634
Source
Medline
License
Unknown

Abstract

Adipocytes have been viewed as a space-filler in bone marrow for a long time. However, a recent study (Naveiras et al., 2009. Nature 460, 259-263) shows that adipocytes are microenvironmental components that suppress hematopoiesis under homeostatic and especially stressed conditions.

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