Pediatric nursing has long neglected the important topic of sexuality, supporting the myth that children are asexual. How can we learn about this crucial topic? How can we incorporate sexuality education into our nursing care in a respectful and supportive manner? How can we honor the whole person, including the sexual self? This article addresses the need for sexuality education for children with chronic conditions and their families; describes a framework for education for the separate yet inter-relating aspects of sexuality; provides practical pointers for nurses to include sexuality education in their client care; and identifies sources of information for health care providers and families.