Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

Authors

• Lagou, Vasiliki^{1, 2, 3}
• Mägi, Reedik⁴
• Hottenga, Jouke- Jan^{5, 6}
• Grallert, Harald^{7, 8}
• Perry, John R. B.⁹
• Bouatia-Naji, Nabila^{10, 11, 12}
• Marullo, Letizia¹³
• Rybin, Denis¹⁴
• Jansen, Rick¹⁵
• Min, Josine L.^{16, 17}
• Dimas, Antigone S.¹⁸
• Ulrich, Anna¹⁹
• Zudina, Liudmila¹⁹
• Gådin, Jesper R.²⁰
• Jiang, Longda^{19, 21}
• Faggian, Alessia¹⁹
• Bonnefond, Amélie^{10, 11, 19}
• Fadista, Joao²²
• Stathopoulou, Maria G.²³
• Isaacs, Aaron^{24, 25, 25}
• Willems, Sara M.²⁴
• Navarro, Pau²⁶
• Tanaka, Toshiko²⁷
• Jackson, Anne U.²⁸
• Montasser, May E.²⁹
• O’Connell, Jeff R.²⁹
• Bielak, Lawrence F.²⁸
• Webster, Rebecca J.³⁰
• Saxena, Richa^{31, 32, 33, 34}
• Stafford, Jeanette M.³⁵
• Pourcain, Beate St^{16, 17}
• Timpson, Nicholas J.^{16, 17}
• Salo, Perttu³⁶
• Shin, So-Youn³⁷
• Amin, Najaf³⁸
• Smith, Albert V.^{28, 39, 40}
• Li, Guo^{41, 41}
• Verweij, Niek⁴²
• Goel, Anuj^{1, 43}
• Ford, Ian⁴⁴
• Johnson, Paul C. D.^{44, 44}
• Johnson, Toby^{45, 45}
• Kapur, Karen⁴⁶
• Thorleifsson, Gudmar⁴⁷
• Strawbridge, Rona J.^{48, 49, 44}
• Rasmussen-Torvik, Laura J.⁵⁰
• Esko, Tõnu⁴
• Mihailov, Evelin⁴
• Fall, Tove⁵¹
• Fraser, Ross M.^{52, 53}
• Mahajan, Anubha^{1, 54}
• Kanoni, Stavroula^{45, 55}
• Giedraitis, Vilmantas⁵⁶
• Kleber, Marcus E.⁵⁷
• Silbernagel, Günther⁵⁸
• Meyer, Julia⁵⁹
• Müller-Nurasyid, Martina^{59, 60, 61, 62}
• Ganna, Andrea^{63, 64, 64}
• Sarin, Antti-Pekka^{65, 36}
• Yengo, Loic^{10, 11, 21}
• Shungin, Dmitry^{66, 67, 66}
• Luan, Jian’an⁹
• Horikoshi, Momoko^{1, 43, 68}
• An, Ping⁶⁹
• Sanna, Serena^{70, 71}
• Boettcher, Yvonne^{72, 72}
• Rayner, N. William^{1, 55, 43}
• Nolte, Ilja M.⁷³
• Zemunik, Tatijana⁷⁴
• Iperen, Erik van⁷⁵
• Kovacs, Peter⁷²
• Hastie, Nicholas D.²⁶
• Wild, Sarah H.⁵²
• McLachlan, Stela⁵²
• Campbell, Susan²⁶
• Polasek, Ozren⁷⁴
• Carlson, Olga⁷⁶
• Egan, Josephine⁷⁶
• Kiess, Wieland^{72, 72}
• Willemsen, Gonneke⁵
• Kuusisto, Johanna⁷⁷
• Laakso, Markku⁷⁷
• Dimitriou, Maria⁷⁸
• Hicks, Andrew A.⁷⁹
• Rauramaa, Rainer^{80, 81}
• Bandinelli, Stefania⁸²
• Thorand, Barbara^{8, 59}
• Liu, Yongmei³⁵
• Miljkovic, Iva⁸³
• Lind, Lars⁸⁴
• Doney, Alex⁸⁵
• Perola, Markus^{36, 65, 4}
• Hingorani, Aroon⁸⁶
• Kivimaki, Mika⁸⁶
• Kumari, Meena^{86, 87}
• Bennett, Amanda J.⁴³
• Groves, Christopher J.⁴³
• Herder, Christian^{8, 88, 89}
• Koistinen, Heikki A.^{90, 91, 92}
• Kinnunen, Leena⁹⁰
• Faire, Ulf de⁴⁸
• Bakker, Stephan J. L.⁷³
• Uusitupa, Matti⁹³
• Palmer, Colin N. A.⁸⁵
• Jukema, J. Wouter^{94, 95}
• Sattar, Naveed⁹⁶
• Pouta, Anneli^{36, 97}
• Snieder, Harold⁷³
• Boerwinkle, Eric^{98, 99}
• Pankow, James S.¹⁰⁰
• Magnusson, Patrik K.⁴⁸
• Krus, Ulrika¹⁰¹
• Scapoli, Chiara¹³
• de Geus, Eco J. C. N.^{5, 6}
• Blüher, Matthias^{72, 102}
• Wolffenbuttel, Bruce H. R.⁷³
• Province, Michael A.⁶⁹
• Abecasis, Goncalo R.²⁸
• Meigs, James B.^{64, 103, 33}
• Hovingh, G. Kees^{104, 105}
• Lindström, Jaana¹⁰⁶
• Wilson, James F.^{26, 52}
• Wright, Alan F.²⁶
• Dedoussis, George V.⁷⁸
• Bornstein, Stefan R.¹⁰⁷
• Schwarz, Peter E. H.^{108, 109, 110}
• Tönjes, Anke^{72, 72}
• Winkelmann, Bernhard R.¹¹¹
• Boehm, Bernhard O.¹¹²
• März, Winfried^{57, 113}
• Metspalu, Andres⁴
• Price, Jackie F.⁵²
• Deloukas, Panos^{45, 55, 114}
• Körner, Antje^{72, 63}
• Lakka, Timo A.^{80, 115}
• Keinanen-Kiukaanniemi, Sirkka M.^{116, 117}
• Saaristo, Timo E.^{118, 119}
• Bergman, Richard N.¹²⁰
• Tuomilehto, Jaakko^{36, 65, 121, 114}
• Wareham, Nicholas J.⁹
• Langenberg, Claudia⁹
• Männistö, Satu⁹⁰
• Franks, Paul W.^{67, 122, 66}
• Hayward, Caroline²⁶
• Vitart, Veronique²⁶
• Kaprio, Jaakko^{65, 65}
• Visvikis-Siest, Sophie²³
• Balkau, Beverley^{123, 124}
• Altshuler, David^{31, 32, 33}
• Rudan, Igor⁵²
• Stumvoll, Michael^{72, 72}
• Campbell, Harry⁵²
• van Duijn, Cornelia M.^{24, 125}
• Gieger, Christian^{7, 8, 59}
• Illig, Thomas^{7, 126, 126}
• Ferrucci, Luigi¹²⁷
• Pedersen, Nancy L.⁴⁸
• Pramstaller, Peter P.^{79, 128, 129}
• Boehnke, Michael²⁸
• Frayling, Timothy M.¹³⁰
• Shuldiner, Alan R.^{29, 131}
• Peyser, Patricia A.²⁸
• Kardia, Sharon L. R.²⁸
• Palmer, Lyle J.¹³²
• Penninx, Brenda W.¹⁵
• Meneton, Pierre¹³³
• Harris, Tamara B.¹³⁴
• Navis, Gerjan⁷³
• Harst, Pim van der^{42, 135}
• Smith, George Davey¹⁶
• Forouhi, Nita G.⁹
• Loos, Ruth J. F.^{9, 136}
• Salomaa, Veikko³⁶
• Soranzo, Nicole³⁷
• Boomsma, Dorret I.⁵
• Groop, Leif^{65, 101}
• Tuomi, Tiinamaija^{65, 101, 137, 138}
• Hofman, Albert^{38, 139, 140}
• Munroe, Patricia B.^{45, 45}
• Gudnason, Vilmundur^{39, 141}
• Siscovick, David S.^{41, 41, 41}
• Watkins, Hugh^{1, 43}
• Lecoeur, Cecile^{10, 11}
• Vollenweider, Peter¹⁴²
• Franco-Cereceda, Anders⁴⁸
• Eriksson, Per²⁰
• Jarvelin, Marjo-Riitta^{19, 116}
• Stefansson, Kari^{47, 143}
• Hamsten, Anders^{48, 49, 49}
• Nicholson, George⁴³
• Karpe, Fredrik^{43, 144}
• Dermitzakis, Emmanouil T.¹⁴⁵
• Lindgren, Cecilia M.^{1, 31, 43, 43}
• McCarthy, Mark I.^{1, 43, 144, 54}
• Froguel, Philippe^{10, 11, 19}
• Kaakinen, Marika A.^{19, 146}
• Lyssenko, Valeriya^{101, 147}
• Watanabe, Richard M.^{102, 102, 148}
• Ingelsson, Erik^{51, 149, 150}
• Florez, Jose C.^{32, 63}
• Dupuis, Josée¹⁵¹
• Barroso, Inês^{37, 152, 153}
• Morris, Andrew P.^{1, 4, 154, 155}
• Prokopenko, Inga^{1, 19, 43, 146, 156}
And 184 more

• ¹ University of Oxford, Oxford, United Kingdom , Oxford (United Kingdom)
• ² Laboratory of Adaptive Immunity, Leuven, KU Leuven, Belgium , Leuven (Belgium)
• ³ VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium , Leuven (Belgium)
• ⁴ University of Tartu, Tartu, Estonia , Tartu (Estonia)
• ⁵ Vrije Universiteit, Amsterdam, the Netherlands , Amsterdam (Netherlands)
• ⁶ VU University medical center, Amsterdam, the Netherlands , Amsterdam (Netherlands)
• ⁷ Helmholtz Zentrum München Research Center for Environmental Health, Neuherberg, Germany , Neuherberg (Germany)
• ⁸ German Center for Diabetes Research (DZD, München-Neuherberg, Germany , München-Neuherberg (Germany)
• ⁹ University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom , Cambridge (United Kingdom)
• ¹⁰ University of Lille Nord de France, Lille, France , Lille (France)
• ¹¹ CNRS UMR8199, Institut Pasteur de Lille, Lille, France , Lille (France)
• ¹² INSERM U970, Paris Cardiovascular Research Center PARCC, Paris, 75006, France , Paris (France)
• ¹³ University of Ferrara, Ferrara, Italy , Ferrara (Italy)
• ¹⁴ Boston University Data Coordinating Center, Boston, MA, USA , Boston (United States)
• ¹⁵ VU University Medical Center, Amsterdam, the Netherlands , Amsterdam (Netherlands)
• ¹⁶ University of Bristol, Bristol, UK , Bristol (United Kingdom)
• ¹⁷ University of Bristol, Bristol, United Kingdom , Bristol (United Kingdom)
• ¹⁸ Biomedical Sciences Research Center Al. Fleming, Vari, Greece , Vari (Greece)
• ¹⁹ Imperial College London, London, UK , London (United Kingdom)
• ²⁰ Karolinska University Hospital, Solna, Sweden , Solna (Sweden)
• ²¹ The University of Queensland, Brisbane, QLD, 4072, Australia , Brisbane (Australia)
• ²² Statens Serum Institut, Copenhagen, Denmark , Copenhagen (Denmark)
• ²³ Université de Lorraine, IGE-PCV, Nancy, F-54000, France , Nancy (France)
• ²⁴ Erasmus Medical Center, Rotterdam, the Netherlands , Rotterdam (Netherlands)
• ²⁵ Maastricht University, Maastricht, the Netherlands , Maastricht (Netherlands)
• ²⁶ University of Edinburgh, Western General Hospital, Edinburgh, UK , Edinburgh (United Kingdom)
• ²⁷ National Institute on Aging, Baltimore, MD, USA , Baltimore (United States)
• ²⁸ University of Michigan, Ann Arbor, MI, USA , Ann Arbor (United States)
• ²⁹ University of Maryland, School of Medicine, Baltimore, MD, USA , Baltimore (United States)
• ³⁰ University of Western Australia Centre for Medical Research, Nedlands, WA, Australia , Nedlands (Australia)
• ³¹ Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, MA, USA , Cambridge (United States)
• ³² Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA , Boston (United States)
• ³³ Harvard Medical School, Boston, MA, USA , Boston (United States)
• ³⁴ Critical Care and Pain Medicine, MGH, Boston, MA, USA , Boston (United States)
• ³⁵ Wake Forest University School of Medicine, Winston-Salem, NC, USA , Winston-Salem (United States)
• ³⁶ Finnish Institute for Health and Welfare, Helsinki, Finland , Helsinki (Finland)
• ³⁷ Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK , Hinxton (United Kingdom)
• ³⁸ Department of Epidemiology Erasmus MC, Rotterdam, the Netherlands , Rotterdam (Netherlands)
• ³⁹ Icelandic Heart Association, Kopavogur, Iceland , Kopavogur (Iceland)
• ⁴⁰ University of Iceland, Reykjavik, Iceland , Reykjavik (Iceland)
• ⁴¹ University of Washington, Seattle, WA, USA , Seattle (United States)
• ⁴² University of Groningen, University Medical Center Groningen, Groningen, The Netherlands , Groningen (Netherlands)
• ⁴³ University of Oxford, Oxford, UK , Oxford (United Kingdom)
• ⁴⁴ University of Glasgow, Glasgow, UK , Glasgow (United Kingdom)
• ⁴⁵ Queen Mary University of London, London, UK , London (United Kingdom)
• ⁴⁶ University of Lausanne, Lausanne, Switzerland , Lausanne (Switzerland)
• ⁴⁷ deCODE Genetics, Reykjavik, Iceland , Reykjavik (Iceland)
• ⁴⁸ Karolinska Institutet, Stockholm, Sweden , Stockholm (Sweden)
• ⁴⁹ Karolinska University Hospital Solna, Stockholm, Sweden , Stockholm (Sweden)
• ⁵⁰ Northwestern University Feinberg School of Medicine, Chicago, IL, USA , Chicago (United States)
• ⁵¹ Uppsala University, Uppsala, Sweden , Uppsala (Sweden)
• ⁵² University of Edinburgh, Edinburgh, UK , Edinburgh (United Kingdom)
• ⁵³ Synpromics Ltd, Roslin Innovation Centre, Easter Bush Campus, Edinburgh, EH25 9RG, UK , Edinburgh (United Kingdom)
• ⁵⁴ Genentech, 340 Point San Bruno Boulevard, South San Francisco, CA, 94080, USA , South San Francisco (United States)
• ⁵⁵ Wellcome Trust Sanger Institute, Hinxton, UK , Hinxton (United Kingdom)
• ⁵⁶ Uppsala Universitet, Uppsala, Sweden , Uppsala (Sweden)
• ⁵⁷ Heidelberg University, Mannheim, Germany , Mannheim (Germany)
• ⁵⁸ Medical University of Graz, Graz, Austria , Graz (Austria)
• ⁵⁹ German Research Center for Environmental Health, Neuherberg, Germany , Neuherberg (Germany)
• ⁶⁰ Ludwig-Maximilians-Universität, Munich, Germany , Munich (Germany)
• ⁶¹ University Hospital Grosshadern, Ludwig-Maximilians-University, Munich, Germany , Munich (Germany)
• ⁶² Johannes Gutenberg University, Mainz, 55101, Germany , Mainz (Germany)
• ⁶³ Massachusetts General Hospital, Boston, MA, USA , Boston (United States)
• ⁶⁴ Broad Institute of MIT and Harvard, Cambridge, MA, USA , Cambridge (United States)
• ⁶⁵ University of Helsinki, Helsinki, Finland , Helsinki (Finland)
• ⁶⁶ Umeå University, Umeå, Sweden , Umeå (Sweden)
• ⁶⁷ Skåne University Hospital Malmö, Malmö, Sweden , Malmö (Sweden)
• ⁶⁸ RIKEN, Center for Integrative Medical Sciences, Laboratory for Endocrinology, Metabolism and Kidney Disease, Yokohama, Japan , Yokohama (Japan)
• ⁶⁹ Washington University School of Medicine, St. Louis, MO, USA , St. Louis (United States)
• ⁷⁰ Istituto di Ricerca Genetica e Biomedica, CNR, Monserrato, Italy , Monserrato (Italy)
• ⁷¹ University of Groningen, Groningen, the Netherlands , Groningen (Netherlands)
• ⁷² University of Leipzig, Leipzig, Germany , Leipzig (Germany)
• ⁷³ University of Groningen, University Medical Center Groningen, Groningen, the Netherlands , Groningen (Netherlands)
• ⁷⁴ University of Split, Split, Croatia , Split (Croatia)
• ⁷⁵ University of Amsterdam, Amsterdam, the Netherlands , Amsterdam (Netherlands)
• ⁷⁶ National Institute of Aging, Baltimore, MD, USA , Baltimore (United States)
• ⁷⁷ University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland , Kuopio (Finland)
• ⁷⁸ Harokopio University, Athens, Greece , Athens (Greece)
• ⁷⁹ European Academy Bozen/Bolzano (EURAC) (Affiliated Institute of the University of LübeckLübeckGermany), Bolzano, Italy , Bolzano (Italy)
• ⁸⁰ Kuopio Research Institute of Exercise Medicine, Kuopio, Finland , Kuopio (Finland)
• ⁸¹ Kuopio University Hospital, Kuopio, Finland , Kuopio (Finland)
• ⁸² Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy , Florence (Italy)
• ⁸³ University of Pittsburgh, Pittsburgh, PA, USA , Pittsburgh (United States)
• ⁸⁴ Uppsala University, Akademiska sjukhuset, Uppsala, Sweden , Uppsala (Sweden)
• ⁸⁵ University of Dundee, Dundee, UK , Dundee (United Kingdom)
• ⁸⁶ University College London, London, UK , London (United Kingdom)
• ⁸⁷ University of Essex, Wivenhoe Park, Colchester, Essex, UK , Colchester (United Kingdom)
• ⁸⁸ Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany , Düsseldorf (Germany)
• ⁸⁹ Heinrich Heine University Düsseldorf, Düsseldorf, Germany , Düsseldorf (Germany)
• ⁹⁰ Finnish Institute for Health and Welfare, Helsinki, FI-00271, Finland , Helsinki (Finland)
• ⁹¹ University of Helsinki and Helsinki University Central Hospital, Haartmaninkatu 4, Helsinki, FI-00029, Finland , Helsinki (Finland)
• ⁹² Minerva Foundation Institute for Medical Research, Biomedicum 2U, Tukholmankatu 8, Helsinki, FI-00290, Finland , Helsinki (Finland)
• ⁹³ University of Eastern Finland, Kuopio, Finland , Kuopio (Finland)
• ⁹⁴ Leiden University Medical Center, Leiden, the Netherlands , Leiden (Netherlands)
• ⁹⁵ Netherlands Heart Institute, Utrecht, the Netherlands , Utrecht (Netherlands)
• ⁹⁶ University of Glasgow, Glasgow, United Kingdom , Glasgow (United Kingdom)
• ⁹⁷ Oulu University Hospital and University of Oulu, Oulu, Finland , Oulu (Finland)
• ⁹⁸ IMM Center for Human Genetics, University of Texas Health Science Center at Houston, Houston, TX, USA , Houston (United States)
• ⁹⁹ University of Texas Health Science Center at Houston, Houston, TX, USA , Houston (United States)
• ¹⁰⁰ University of Minnesota, Minneapolis, MiI, USA , Minneapolis (United States)
• ¹⁰¹ University Hospital Malmö, Lund University, Malmö, Sweden , Malmö (Sweden)
• ¹⁰² Keck School of Medicine of USC, Los Angeles, CA, USA , Los Angeles (United States)
• ¹⁰³ General Medicine Division, Massachusetts General Hospital, Boston, MA, USA , Boston (United States)
• ¹⁰⁴ Amsterdam UMC, Amsterdam, the Netherlands , Amsterdam (Netherlands)
• ¹⁰⁵ Novo Nordisk A/S, Copenhagen, Denmark , Copenhagen (Denmark)
• ¹⁰⁶ Diabetes Prevention Unit, Helsinki, Finland , Helsinki (Finland)
• ¹⁰⁷ Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany , Dresden (Germany)
• ¹⁰⁸ Technische Universität Dresden, Dresden, Germany , Dresden (Germany)
• ¹⁰⁹ Paul Langerhans Institute Dresden of the Helmholtz Center Munich at University Hospital and Faculty of Medicine, TU Dresden, Dresden, Germany , Dresden (Germany)
• ¹¹⁰ German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany , Neuherberg (Germany)
• ¹¹¹ Cardiology Group, Frankfurt-Sachsenhausen, Germany , Frankfurt-Sachsenhausen (Germany)
• ¹¹² Nanyang Technological University Singapore and Imperial College London, Singapore, Singapore , Singapore (Singapore)
• ¹¹³ Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany , Mannheim (Germany)
• ¹¹⁴ King Abdulaziz University, Jeddah, Saudi Arabia , Jeddah (Saudi Arabia)
• ¹¹⁵ University of Eastern Finland, Kuopio Campus, Kuopio, Finland , Kuopio (Finland)
• ¹¹⁶ University of Oulu, Oulu, Finland , Oulu (Finland)
• ¹¹⁷ Oulu University Hospital, Oulu, Finland , Oulu (Finland)
• ¹¹⁸ Finnish Diabetes Association, Tampere, Finland , Tampere (Finland)
• ¹¹⁹ Pirkanmaa Hospital District, Tampere, Finland , Tampere (Finland)
• ¹²⁰ Cedars-Sinai Medical Center, Los Angeles, CA, USA , Los Angeles (United States)
• ¹²¹ Danube-University Krems, Krems, Austria , Krems (Austria)
• ¹²² Harvard School of Public Health, Boston, MA, USA , Boston (United States)
• ¹²³ Inserm, CESP Center for Research in Epidemiology and Public Health, Villejuif, U1018, France , Villejuif (France)
• ¹²⁴ Univ Paris-Saclay, Univ Paris Sud, UVSQ, UMRS 1018, UMRS 1018, Villejuif, France , Villejuif (France)
• ¹²⁵ Centre for Medical Systems Biology, Leiden, the Netherlands , Leiden (Netherlands)
• ¹²⁶ Hannover Medical School, Hannover, Germany , Hannover (Germany)
• ¹²⁷ National Institute on Aging, Baltimore, Maryland, USA , Baltimore (United States)
• ¹²⁸ General Central Hospital, Bolzano, Italy , Bolzano (Italy)
• ¹²⁹ University of Lübeck, Lübeck, Germany , Lübeck (Germany)
• ¹³⁰ University of Exeter, Exeter, UK , Exeter (United Kingdom)
• ¹³¹ Regeneron Pharmaceuticals, Tarrytown, NY, USA , Tarrytown (United States)
• ¹³² University of Adelaide, Adelaide, Australia , Adelaide (Australia)
• ¹³³ Centre de Recherche des Cordeliers, Paris, 75006, France , Paris (France)
• ¹³⁴ National Institute on Aging, Bethesda, MD, USA , Bethesda (United States)
• ¹³⁵ University Medical Center Groningen, University of Groningen, Groningen, the Netherlands , Groningen (Netherlands)
• ¹³⁶ Icahn School of Medicine at Mount Sinai, New York, NY, USA , New York (United States)
• ¹³⁷ University of Helsinki and Helsinki University Hospital, Helsinki, Finland , Helsinki (Finland)
• ¹³⁸ University of Helsinki and Folkhälsan Research Center, Helsinki, Finland , Helsinki (Finland)
• ¹³⁹ Netherlands Consortium for healthy ageing, the Hague, the Netherlands , the Hague (Netherlands)
• ¹⁴⁰ Harvard T.H. Chan School of Public Health, Boston, USA , Boston (United States)
• ¹⁴¹ Faculty of Medicine University of Iceland, Reykjavik, Iceland , Reykjavik (Iceland)
• ¹⁴² University Hospital Lausanne, Lausanne, Switzerland , Lausanne (Switzerland)
• ¹⁴³ University of Iceland, Reykjavík, Iceland , Reykjavík (Iceland)
• ¹⁴⁴ Churchill Hospital, Oxford, UK , Oxford (United Kingdom)
• ¹⁴⁵ University of Geneva Medical School, Geneva, Switzerland , Geneva (Switzerland)
• ¹⁴⁶ University of Surrey, Guildford, UK , Guildford (United Kingdom)
• ¹⁴⁷ University of Bergen, Bergen, Norway , Bergen (Norway)
• ¹⁴⁸ USC Diabetes and Obesity Research Institute, Los Angeles, CA, USA , Los Angeles (United States)
• ¹⁴⁹ Stanford University School of Medicine, Stanford, CA, USA , Stanford (United States)
• ¹⁵⁰ Stanford University, Stanford, CA, 94305, USA , Stanford (United States)
• ¹⁵¹ Boston University School of Public Health, Boston, MA, USA , Boston (United States)
• ¹⁵² Wellcome Trust-MRC Institute of Metabolic Science, Cambridge, UK , Cambridge (United Kingdom)
• ¹⁵³ University of Exeter Medical School, Exeter, UK , Exeter (United Kingdom)
• ¹⁵⁴ University of Liverpool, Liverpool, UK , Liverpool (United Kingdom)
• ¹⁵⁵ The University of Manchester, Manchester, UK , Manchester (United Kingdom)
• ¹⁵⁶ Ufa Federal Research Centre Russian Academy of Sciences, Ufa, Russian Federation , Ufa (Russia)

Type

Published Article

Journal

Nature Communications

Publisher

Springer Nature

Publication Date

Jan 05, 2021

Volume

12

Issue

1

Identifiers

DOI: 10.1038/s41467-020-19366-9

Source

Springer Nature

License

Green