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Sex differences in immune responses to infectious diseases

Authors
  • Fischer, Julia1, 2, 3
  • Jung, Norma1
  • Robinson, Nirmal4, 2
  • Lehmann, Clara1, 3
  • 1 University of Cologne, First Department of Internal Medicine, Kerpener Str. 62, Cologne, 50934, Germany , Cologne (Germany)
  • 2 CECAD Research Center, Cologne, Germany , Cologne (Germany)
  • 3 German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany , Cologne (Germany)
  • 4 University of Cologne, Institute for Medical Microbiology, Immunology and Hygiene, Cologne, Germany , Cologne (Germany)
Type
Published Article
Journal
Infection
Publisher
Springer-Verlag
Publication Date
May 09, 2015
Volume
43
Issue
4
Pages
399–403
Identifiers
DOI: 10.1007/s15010-015-0791-9
Source
Springer Nature
Keywords
License
Yellow

Abstract

PurposeThe influence of sex hormones is recognized to account for the susceptibility and distinct outcomes of diverse infectious diseases.MethodsThis review discusses several variables including differences in behavior and exposure to pathogens, genetic, and immunological factors.ConclusionUnderstanding sex-based differences in immunity during different infectious diseases is crucial in order to provide optimal disease management for both sexes.

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