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Severe hyperventilation and respiratory alkalosis during pressure-support ventilation: report of a hazard.

Authors
Type
Published Article
Journal
Anaesthesia
Publication Date
Volume
50
Issue
11
Pages
978–980
Identifiers
PMID: 8678256
Source
Medline
License
Unknown

Abstract

A 53-year-old woman with a flaccid quadriparesis developed severe hyperventilation and respiratory alkalosis during pressure-support ventilation. A gas leak in the ventilator system caused a loss of positive end-expiratory pressure and autocycling of the ventilator. Large ventilator breaths were then delivered because a high level of pressure support was set in a patient with low respiratory impedance. The complication is rare and its occurrence requires a combination of patient and equipment factors. Awareness of the responsible factors will promote detection and prevention of the hazard.

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