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Severe Generalized Bullous Fixed Drug Eruption Treated with Cyclosporine: A Case Report and Literature Review

Authors
  • Barootes, Hailey C.
  • Peebles, Erin R.
  • Matsui, Doreen
  • Rieder, Michael
  • Abuzgaia, Awatif
  • Mohammed, Javed A.
Type
Published Article
Journal
Case Reports in Dermatology
Publisher
S. Karger AG
Publication Date
Mar 03, 2021
Volume
13
Issue
1
Pages
154–163
Identifiers
DOI: 10.1159/000513469
PMID: 33790760
PMCID: PMC7989674
Source
Karger
Keywords
License
Green
External links

Abstract

Generalized bullous fixed drug eruptions (GBFDEs) are rare in the paediatric population. We present the case of a 7-year-old girl with GBFDE believed to be secondary to oral ibuprofen, who experienced rapid resolution of lesions and cessation of blistering with a 3-week course of oral cyclosporine. To the best of our knowledge, this is the first report of a paediatric case of GBFDE treated with cyclosporine. In our report, we review published cases of GBFDE in children, and all adult cases managed with cyclosporine.

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