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[Severe form of Rotavirus infection during the period of seasonal rise of its incidence].

Authors
Type
Published Article
Journal
Pediatriia
Publication Date
Issue
7
Pages
35–40
Identifiers
PMID: 2780158
Source
Medline
License
Unknown

Abstract

The authors describe the results of observation and clinico-laboratory examination of patients during seasonal rises of the rotavirus infection incidence in 5 districts of the Moscow region in 1984-1987. The diseases ran their courses in the form of gastroenteritis and enteritis and were marked by a great number of the grave patterns (42-46%), mainly in children of the first three years of life, by a high percentage (77.5%) of the aggravated premorbid status of patients with the grave patterns. The rotavirus nature of diarrheas was supported by the data of direct electron microscopy, ELISA, and solid-phase coagglutination test. The symptom-complex of the clinical manifestations of rotavirus infection was characterized in detail. The histologic and morphometric data pertaining to two lethal outcomes were discussed. It has been demonstrated that respiratory viral infections, primarily influenza, produced an adverse effect, promoting the formation of the severe patterns and the onset of unfavourable outcomes of rotavirus infection in children.

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