Affordable Access

Severe or fatal liver injury in 50 patients in the United States taking rifampin and pyrazinamide for latent tuberculosis infection.

Authors
  • Ijaz, Kashef
  • Jereb, John A
  • Lambert, Lauren A
  • Bower, William A
  • Spradling, Philip R
  • McElroy, Peter D
  • Iademarco, Michael F
  • Navin, Thomas R
  • Castro, Kenneth G
Type
Published Article
Journal
Clinical Infectious Diseases
Publisher
Oxford University Press
Publication Date
Feb 01, 2006
Volume
42
Issue
3
Pages
346–355
Identifiers
PMID: 16392079
Source
Medline
License
Unknown

Abstract

RZ was the likeliest cause of most of these liver injuries, some of which were fatal in spite of monitoring. Fatality was predicted by age or use of other medications, but none of the cofactors showed promise as a reliable clinical predictor of severe liver injury.

Report this publication

Statistics

Seen <100 times