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Severe Coronavirus Disease-2019 in Children and Young Adults in the Washington, DC, Metropolitan Region

Authors
  • DeBiasi, Roberta L.1, 2, 3
  • Song, Xiaoyan2, 4
  • Delaney, Meghan2, 5
  • Bell, Michael2, 6
  • Smith, Karen2, 7
  • Pershad, Jay2, 8
  • Ansusinha, Emily1
  • Hahn, Andrea1, 2
  • Hamdy, Rana1, 2
  • Harik, Nada1, 2
  • Hanisch, Benjamin1, 2
  • Jantausch, Barbara1, 2
  • Koay, Adeline1, 2
  • Steinhorn, Robin2, 9
  • Newman, Kurt2, 10
  • Wessel, David2, 6
  • 1 Division of Pediatric Infectious Diseases, Children's National Hospital, Washington, DC
  • 2 Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, DC
  • 3 Department of Microbiology, Immunology and Tropical Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC
  • 4 Division of Infection Control and Epidemiology, Children's National Hospital, Washington, DC
  • 5 Division of Laboratory Medicine and Pathology, Children's National Hospital, Washington, DC
  • 6 Division of Critical Care Medicine, Children's National Hospital, Washington, DC
  • 7 Division of Hospitalist Medicine, Children's National Hospital, Washington, DC
  • 8 Division of Emergency Medicine, Children's National Hospital, Washington, DC
  • 9 Division of Neonatology, Children's National Hospital, Washington, DC
  • 10 Chief Executive Officer, Division of Pediatric Surgery, Children's National Hospital, Washington, DC
Type
Published Article
Journal
The Journal of Pediatrics
Publisher
Elsevier Inc.
Publication Date
May 13, 2020
Volume
223
Pages
199–203
Identifiers
DOI: 10.1016/j.jpeds.2020.05.007
PMID: 32405091
PMCID: PMC7217783
Source
PubMed Central
Keywords
License
Unknown

Abstract

Despite worldwide spread of severe acute respiratory syndrome coronavirus-2, few publications have reported the potential for severe disease in the pediatric population. We report 177 infected children and young adults, including 44 hospitalized and 9 critically ill patients, with a comparison of patient characteristics between infected hospitalized and nonhospitalized cohorts, as well as critically ill and noncritically ill cohorts. Children <1 year and adolescents and young adults >15 years of age were over-represented among hospitalized patients ( P  = .07). Adolescents and young adults were over-represented among the critically ill cohort ( P  = .02).

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