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Severe cerebral white matter involvement in a case of dentatorubropallidoluysian atrophy studied at autopsy.

Authors
  • Muñoz, Esteban
  • Campdelacreu, Jaume
  • Ferrer, Isidre
  • Rey, María J
  • Cardozo, Adriana
  • Gómez, Beatriz
  • Tolosa, Eduardo
Type
Published Article
Journal
Archives of Neurology
Publisher
American Medical Association
Publication Date
May 2004
Volume
61
Issue
6
Pages
946–949
Identifiers
PMID: 15210537
Source
Medline
License
Unknown

Abstract

Leukoencephalopathy could be a prominent finding in some patients with DRPLA, explaining, at least in part, their clinical evolution. In our case, the disproportion between the severity of white matter damage and vascular changes does not support a cardinal role for ischemic mechanisms in leukoencephalopathy.

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