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Severe atypical neuropathy associated with administration of hematopoietic colony-stimulating factors and vincristine.

Authors
  • Weintraub, M
  • Adde, M A
  • Venzon, D J
  • Shad, A T
  • Horak, I D
  • Neely, J E
  • Seibel, N L
  • Gootenberg, J
  • Arndt, C
  • Nieder, M L
  • Magrath, I T
Type
Published Article
Journal
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Publication Date
Mar 01, 1996
Volume
14
Issue
3
Pages
935–940
Identifiers
PMID: 8622042
Source
Medline
License
Unknown

Abstract

Our results indicate that CSFs can precipitate SAN when given in conjunction with vincristine. The development of SAN was associated most strongly with the cumulative dose of vincristine -- the size of individual doses and the number of doses given in cycle 1 were important to the extent that they influenced the cumulative dose.

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