Affordable Access

Sesquiterpenes from the Vietnamese Marine Sponge Dysidea fragilis.

Authors
  • Cue, Nguyen Thi
  • Anh, Hoang Le Tuan
  • Hang, Dan Thi Thuy
  • Nhiem, Nguyen Xuan
  • Dang, Nguyen Hai
  • Nama, Nguyen Hoai
  • Yen, Pham Hai
  • Thung, Do Cong
  • Thuc, Vu Kim
  • Minh, Chan Van
  • Kiema, Phan Van
Type
Published Article
Journal
Natural product communications
Publication Date
Aug 01, 2015
Volume
10
Issue
8
Pages
1341–1342
Identifiers
PMID: 26434109
Source
Medline
License
Unknown

Abstract

Two new sesquiterpenes, named dysinidins A-B (3, 4) along with two known sesquiterpenes, furodysinin lactone (1) and O-methyl urodysinin lactone (2), were isolated from the Vietnamese marine sponge Dysidea fragilis. Their structures were determined by ID- and 2D-NMR spectroscopies and HR ESI MS, as well as by comparison with reported literature data. None of compounds showed inhibitory growth of human lung cancer cell lines, A-549 and H-1975 (IC50 > 30 μM).

Report this publication

Statistics

Seen <100 times