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Sesaminol prevents Parkinson's disease by activating the Nrf2-ARE signaling pathway

Authors
  • Kaji, Haruka1
  • Matsui-Yuasa, Isao1
  • Matsumoto, Kayo1
  • Omura, Ayano2
  • Kiyomoto, Kunio2
  • Kojima-Yuasa, Akiko1
  • 1 Department of Food and Human Health Sciences, Graduate School of Human Life Science, Osaka City University, 3-3-138 Sugimoto, Sumiyoshi-ku, Osaka, 558-8585, Japan
  • 2 Kiyomoto Co., Ltd., 6-1633 Totoro-cho, Nobeoka, Miyazaki, 889-0595, Japan
Type
Published Article
Journal
Heliyon
Publisher
Elsevier
Publication Date
Nov 02, 2020
Volume
6
Issue
11
Identifiers
DOI: 10.1016/j.heliyon.2020.e05342
PMID: 33163674
PMCID: PMC7609457
Source
PubMed Central
Keywords
License
Unknown

Abstract

Neuroscience; Nutrition; Natural product; Oxidative stress; Antioxidant; Sesaminol; Parkinson's disease; 6-Hydroxydopamine; Rotenone, SH-SY5Y cells; Nrf2

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