Serum stimulation and cell density regulate the proliferation of AsPC-1 cells through control of cyclin E and p27KIP1 expression.

J Horiguchi-Yamada; S Yoshida; A Kuhara; T Aoki; T Ohno; H Yamada

Serum stimulation and cell density regulate the proliferation of AsPC-1 cells through control of cyclin E and p27KIP1 expression.

Authors

Horiguchi-Yamada, J
Yoshida, S
Kuhara, A
Aoki, T
Ohno, T
Yamada, H

Type

Published Article

Journal

Anticancer research

Publication Date

Jan 01, 2001

Volume

21

Issue

3B

Pages

1885–1891

Identifiers

PMID: 11497273

Source

Medline

License

Unknown

Abstract

The proliferation of AsPC-1 cells was still controlled by cell density and serum stimulation; nevertheless, the cells possessed several oncogenic mutations. These results may provide a rationale for modifying the growth environment for treatment of pancreatic cancers.

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. This record was last updated on 07/03/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM. The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/11497273

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