Serum stimulation and cell density regulate the proliferation of AsPC-1 cells through control of cyclin E and p27KIP1 expression.
- Authors
- Type
- Published Article
- Journal
- Anticancer research
- Publication Date
- Jan 01, 2001
- Volume
- 21
- Issue
- 3B
- Pages
- 1885–1891
- Identifiers
- PMID: 11497273
- Source
- Medline
- License
- Unknown
Abstract
The proliferation of AsPC-1 cells was still controlled by cell density and serum stimulation; nevertheless, the cells possessed several oncogenic mutations. These results may provide a rationale for modifying the growth environment for treatment of pancreatic cancers.