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Serum level of alpha-N-acetyl-D-glucosaminidase in myocardial infarction in man.

Authors
Type
Published Article
Journal
Research communications in chemical pathology and pharmacology
Publication Date
Volume
31
Issue
2
Pages
331–340
Identifiers
PMID: 7221186
Source
Medline
License
Unknown

Abstract

alpha-N-acetyl-D-glucosaminidase, a lysosomal enzyme essential for the degradation of heparin sulfate, was measured in the sera of normal individuals and of 19 patients with myocardial infarction (MI). Normal individuals maintained a constant level of this enzyme from day to day. In contrast, patients with MI had a 2-3 fold elevation of this enzyme as early as 2 hr after MI. This elevation persisted at least until the creatine phosphokinase-MB had attained maximum activity, usually 6-23 hr after MI and then gradually decreased, returning to normal levels 3-5 days later.

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