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Serum inhibitory factors and E rosettes in chronic renal failure.

Authors
  • Raptopoulou-GiGi, M
  • Kyriakopoulos, G
  • Goulis, G
Type
Published Article
Journal
Thymus
Publication Date
Jan 01, 1980
Volume
1
Issue
4-5
Pages
281–285
Identifiers
PMID: 7445021
Source
Medline
License
Unknown

Abstract

The inhibiting effect of uraemic serum on both normal and uraemic lymphocytes capacity to form E rosettes was studied in 10 uraemic patients and 14 healthy controls. Uraemic serum was found to significantly inhibit E rosette forming cells of normal and uraemic lymphocytes. On the other hand, E rosettes of uraemic patients ranged in normal values after incubation in normal serum. These findings suggest that rosette inhibiting factors are present in uraemia and that uraemic T lymphocyte sheep erythrocyte rosette function is intact.

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