Serum inhibitory factors and E rosettes in chronic renal failure.
- Published Article
- Publication Date
Jan 01, 1980
The inhibiting effect of uraemic serum on both normal and uraemic lymphocytes capacity to form E rosettes was studied in 10 uraemic patients and 14 healthy controls. Uraemic serum was found to significantly inhibit E rosette forming cells of normal and uraemic lymphocytes. On the other hand, E rosettes of uraemic patients ranged in normal values after incubation in normal serum. These findings suggest that rosette inhibiting factors are present in uraemia and that uraemic T lymphocyte sheep erythrocyte rosette function is intact.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/7445021