A quantitative study of raphe-spinal neurons and serotonergic neurons in 3 medullary raphe nuclei in the cat indicates that more than 80% of the raphe-spinal neurons that project to the spinal cord are serotonergic raphe-spinal neurons in each of the nuclei. More than 85% of the descending raphe-spinal neurons in the two caudal nuclei, nucleus raphe pallidus and nucleus raphe obscurus, are serotonergic, whereas 75% of the raphe-spinal neurons in the more rostrally placed nucleus raphe magnus contain serotonin (5-HT). These results are discussed in relation to descending systems containing both neuropeptides and 5-HT and collateralizing to several spinal segments.
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This record was last updated on 07/02/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/3574767