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SEROEPIDEMIOLOGY OF STRONGYLOIDIASIS IN THE PERUVIAN AMAZON

Authors
  • PABLO P. YORI
  • MARGARET KOSEK
  • ROBERT H. GILMAN
  • JULIANNA CORDOVA
  • CARYN BERN
  • CESAR BANDA CHAVEZ
  • MARIBEL PAREDES OLORTEGUI
  • CARMEN MONTALVAN
  • GRACIELA MEZA SANCHEZ
  • BEVELLE WORTHEN
  • JAMES WORTHEN
  • FAY LEUNG
  • CARLOS VIDAL ORÉ
Publication Date
Jan 01, 2006
Source
PMC
Keywords
Disciplines
  • Biology
License
Unknown

Abstract

A stool and serosurvey for Strongyloides stercoralis was conducted in a community in the Peruvian Amazon region. Strongyloidiasis stercoralis was identified in the stool of 69 (8.7%) of 792 participants. Six hundred nine sera were tested using by an enzyme-linked immunosorbent assay (ELISA), which had a sensitivity of 92% and a specificity of 94%; 442 (72%) were positive. In multivariable logistic regression models, having S. stercoralis in stool was associated with hookworm in the same specimen (odds ratio [OR] = 4.44, 95% confidence interval [CI] = 2.02-9.79), occasionally or never wearing shoes (OR = 1.89, 95% CI = 1.10-3.27), and increasing age (OR = 1.012 for each one-year increase, 95% CI = 1.00-1.03). Similarly, occasionally or never wearing shoes (OR = 1.54, 95% CI = 1.01-2.37) and increasing age (OR = 1.04 for each one-year increase, 95% CI = 1.02-1.06) were associated with an increased risk of a positive S. stercoralis ELISA result. The ELISA had a negative predictive value of 98% and is an excellent screening test for strongyloidiasis.

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