Sequence variation within the 5' regulatory regions of the vitamin D binding protein and receptor genes and prostate cancer risk.
Department of Pharmacology and Toxicology, Cancer Prevention and Control Program, James Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, Kentucky.
- Published Article
- Publication Date
Aug 01, 2005
The VDR-5132 T/C SNP, resulting in potential elimination of the GATA-1 transcription factor-binding site, may increase prostate cancer susceptibility in African-Americans. Confirmation of these findings is needed in larger observational studies.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/15717311