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Sequence Learning Induces Selectivity to Multiple Task Parameters in Mouse Somatosensory Cortex

Authors
  • Bale, Michael R.1
  • Bitzidou, Malamati1
  • Giusto, Elena1
  • Kinghorn, Paul1
  • Maravall, Miguel1
  • 1 Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK
Type
Published Article
Journal
Current Biology
Publisher
Cell Press
Publication Date
Feb 08, 2021
Volume
31
Issue
3
Pages
473–485
Identifiers
DOI: 10.1016/j.cub.2020.10.059
PMID: 33186553
PMCID: PMC7883307
Source
PubMed Central
Keywords
Disciplines
  • Article
License
Unknown

Abstract

Bale et al. analyze neuronal activity in layer 2/3 of somatosensory cortex as mice learn to discriminate between a target and a non-target ordered sequence of whisker motion. Neurons reflect task parameters including the learned association between target sequence and licking, rather than refining their tuning to sensory features.

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