Affordable Access

Sequence homology between two immunodiagnostic fusion proteins from Echinococcus multilocularis.

Authors
  • 1
  • 1 Molecular Helminthology Laboratory, Queensland Institute of Medical Research, Bancroft Centre, Australia. , (Australia)
Type
Published Article
Journal
International Journal for Parasitology
0020-7519
Publisher
Elsevier
Publication Date
Volume
22
Issue
6
Pages
831–833
Identifiers
PMID: 1385344
Source
Medline
License
Unknown

Abstract

Serological diagnosis of alveolar hydatid disease using crude parasite antigen is problematical with the result that several groups have addressed the question of specific serodiagnosis using defined native or recombinant antigens. Sequence data are available for two lambda gt 11 cDNA clones, designated EM4 and pEM10, which express E. multilocularis species-specific proteins in immunodiagnostic assays using human sera. Here, we have drawn attention to the extensive similarities between these antigens and have compared their characteristics since both may prove valuable in the future diagnosis of alveolar hydatidosis.

Statistics

Seen <100 times