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Sequence analysis of the glycoprotein 120 coding region of a new human immunodeficiency virus type 1 subtype G strain from Russia.

Authors
  • Bobkov, A
  • Cheingsong-Popov, R
  • Karasyova, N
  • Selimova, L
  • Kravchenko, A
  • Bochkova, M
  • Kazennova, E
  • Ladnaya, N
  • Pokrovsky, V
  • Weber, J
Type
Published Article
Journal
AIDS research and human retroviruses
Publication Date
Sep 20, 1996
Volume
12
Issue
14
Pages
1385–1388
Identifiers
PMID: 8891119
Source
Medline
Keywords
License
Unknown

Abstract

This paper reports the sequencing of HIV-1 subtype G from the blood sample of a 39-year-old Russian male taken in November 1992. The heterosexual, White male and his wife living in Uzbekistan found in 1991 that they were infected with HIV-1. The man reported living in Mozambique during 1984-85 where he had no sexual relations with African residents, yet was admitted to the hospital on several occasions. However, in 1986-87, shortly after returning to the Soviet Union, he reported having a sexual relationship with a woman other than his wife. That woman and her husband were also found to be HIV-positive in 1991. The subject died in November 1993, and his wife in March 1995. His peripheral blood mononuclear cells were separated and kept at -70 degrees Celsius until used. When the blood sample was obtained, the man had a CD4 count of 10 cells/mcl, had lost more than 10% of his weight, and developed candidal esophagitis and chronic diarrhea associated with Cryptosporidia.

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