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Sentinel node detection and radioguided occult lesion localization in breast cancer.

Authors
  • Trifirò, Guiseppe
  • Lavinia Travaini, Laura
  • De Cicco, Concetta
  • Paganelli, Giovanni
Type
Published Article
Journal
Physica Medica
Publisher
Elsevier
Publication Date
Jan 01, 2006
Volume
21 Suppl 1
Pages
20–23
Identifiers
PMID: 17645988
Source
Medline
License
Unknown

Abstract

Sentinel lymph node biopsy might replace complete axillary dissection for staging of the axilla in clinically N0 breast cancer patients and represent a significant advantage as a minimally invasive procedure, considering that about 70% of patients are found to be free from metastatic disease, yet axillary node dissection can lead to significant morbidity. In our Institute, Radioguided Occult Lesion Localization is the standard method to locate non-palpable breast lesions and the gamma probes is very effective in assisting intra-operative localization and removal, as in sentinel node biopsy. The rapid spread of sentinel lymph node biopsy has led to its use in clinical settings previously considered contraindications to sentinel lymph node biopsy. In this contest, we evaluated in a large group of patients possible factors affecting sentinel node detection and the reliability of sentinel lymph node biopsy carried out after large excisional breast biopsy. Our data confirm that a previous breast surgery does not prohibit efficient sentinel lymph node localization and sentinel lymph node biopsy can correctly stage the axialla in these patients.

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