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Sensitization of guinea pigs to levamisole.

Authors
Type
Published Article
Journal
International archives of allergy and applied immunology
Publication Date
Volume
58
Issue
2
Pages
237–240
Identifiers
PMID: 311351
Source
Medline
License
Unknown

Abstract

Levamisole, an anti-helminthic drug used also as an immunostimulating agent, has been found to be a potent skin sensitizer in experimental animal models. Sensitization is associated with marked T-lymphocyte proliferation in the draining lymph node. It is suggested that immunostimulation through increase in the T-lymphocyte population could be a function of the strong sensitization induced by this compound.

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