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Sensitive chiral analysis by capillary electrophoresis.

Authors
Type
Published Article
Journal
Electrophoresis
0173-0835
Publisher
Wiley Blackwell (John Wiley & Sons)
Publication Date
Volume
27
Issue
1
Pages
195–212
Identifiers
PMID: 16421951
Source
Medline

Abstract

In this review, an updated view of the different strategies used up to now to enhance the sensitivity of detection in chiral analysis by CE will be provided to the readers. With this aim, it will include a brief description of the fundamentals and most of the recent applications performed in sensitive chiral analysis by CE using offline and online sample treatment techniques (SPE, liquid-liquid extraction, microdialysis, etc.), on-column preconcentration techniques based on electrophoretic principles (ITP, stacking, and sweeping), and alternative detection systems (spectroscopic, spectrometric, and electrochemical) to the widely used UV-Vis absorption detection.

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